EJONS INTERNATIONAL JOURNAL ON MATHEMATICS, ENGINEERING & NATURAL SCIENCES ISSN 2602 - 4136

Quick Access


Bu Dergi DOI ve Crosscheck üyesidir


Abstract


THROMBOPHILIC GENE MUTATIONS IN PATIENTS WITH RECURRENT PREGNANCY LOSS

Background: Recurrent pregnancy loss (RPL) is caused by different factors, including genetics and thrombophilia. FV LEIDEN, FVR 2, FXIII, ß-FIBRINOGEN , PROTROMBIN, PAI 1, HPA 1, MT 677, MT 1298, ACE, APO E, and APO B have been identified linking to hereditary thrombophilia. Objective: In this study, the effect of 12 factors, FV LEIDEN, FVR 2, FXIII, ß-FIBRINOGEN , PROTROMBIN, PAI 1, HPA 1, MT 677, MT 1298, ACE, APO E, and APO B are statistically evaluated in RPL patients data from recent articles. Materials and methods: In patients with recurrent miscarriage, the polymorphisms in which clotting factor genes were statistically analyzed. In addition, were discussed coagulation genes which relation to other diseases. Results: According to the studies related to this subject, FV LEIDEN (45%), PROTROMBIN (31%), FXIII (89%), ß-FIBRINOGEN (29%), PAI 1 (75%), MT 677 (44%) and MT 1298 (33%) were related to the abortions. Conclusion: Most commonly encounter mutations FV LEIDEN, FVR 2, MT 677, FXIII and ß- FIBRINOGEN genes similarly between country of the world. In this context, it may be useful in patients with RPL to monitor the clotting factors in order to clarify the cause of RPL.



Keywords
Habitual Abortion, Trombophylia, Factor V...



References

Advanced Search


Announcements

    Aralık Sayısı

    VERBİS'E KAYIT S�RELERİ HAKKINDA DUYURU | Kırklareli Ticaret ve ...

    Aralık ayında yayınlanacak Sayımız için  25 Kasım Tarihine kadar çalişmanızı Yükleyebilirsiniz



Address :Kazakh National Women's Pedagogical University, Almatı, Kazakhistan
Telephone :+7 778 921 0336 - 0 534 349 92 73 Fax :
Email :ejonsjournal@gmail.com

Web Yazılım & Programlama Han Yazılım Bilişim Hizmetleri