EJONS INTERNATIONAL JOURNAL ON MATHEMATICS, ENGINEERING & NATURAL SCIENCES ISSN 2602 - 4136

Quick Access


Bu Dergi DOI ve Crosscheck üyesidir


INVESTIGATION OF THE EFFECT OF DICLOFENAC SODIUM AND THYMOQUINONE EXPOSURE IN PREGNANCY ON THE NUMBER OF RAT SPERMATOGONIUM CELLS BY STEREOLOGICAL METHODS
(INVESTIGATION OF THE EFFECT OF DICLOFENAC SODIUM AND THYMOQUINONE EXPOSURE IN PREGNANCY ON THE NUMBER OF RAT SPERMATOGONIUM CELLS BY STEREOLOGICAL METHODS )

Author : Fikret ALTINDAĞ  Murat Cetin RAGBETLİ  
Type :
Printing Year : 2018
Number : 4
Page :
Cite : Fikret ALTINDAĞ Murat Cetin RAGBETLİ, (2018). INVESTIGATION OF THE EFFECT OF DICLOFENAC SODIUM AND THYMOQUINONE EXPOSURE IN PREGNANCY ON THE NUMBER OF RAT SPERMATOGONIUM CELLS BY STEREOLOGICAL METHODS. EJONS INTERNATIONAL JOURNAL ON MATHEMATICS, ENGINEERING - NATURAL SCIENCES, 4, p. . Doi: .
    


Summary


Keywords


Abstract

Diclofenac sodium (DS) is a nonsteroidal antiinflammatory (NSAID) drug that has analgesic, antipyretic and antiinflammatory effect. Thymoquinone, the active constituent of Nigella sativa, has bright yellow crystal. The aim of this study was to investigate the effects of diclofenac sodium and thymoquinone applied in pregnancy on the number of spermatogonium cells by stereological methods. Pregnant rats were separated into Control, Saline (SF), Diclofenac Sodium (DS), Thymoquinone (TQ) and Diclofenac Sodium + Thymoquinone (DS + TQ) groups. DS and TQ was given between days 5and 15 of gestation. At the end of the postnatal tenth week, rats were perfused under anesthesia and the right testes were removed. it was embedded in the paraffin. Sections were examined with light microscope. Stereologically, the physical disector method for total cell number of spermatogonium, and the Cavalieri principle for total testis volume were applied. As a result, diclofenac sodium and thymoquinone not caused a significant change on total cell number of spermatogonium in ten week old rats (p >0.05).



Keywords
Diclofenac sodium, Rat, Spermatogonium, Stereology, Thymoquinone

Advanced Search


Announcements

    Aralık Sayısı

    VERBİS'E KAYIT S�RELERİ HAKKINDA DUYURU | Kırklareli Ticaret ve ...

    Aralık ayında yayınlanacak Sayımız için  25 Kasım Tarihine kadar çalişmanızı Yükleyebilirsiniz



Address :Kazakh National Women's Pedagogical University, Almatı, Kazakhistan
Telephone :+7 778 921 0336 - 0 534 349 92 73 Fax :
Email :ejonsjournal@gmail.com

Web Yazılım & Programlama Han Yazılım Bilişim Hizmetleri